September 1, 2015


How To Comply With New York I-STOP

UPDATE: How to Comply with State Mandates

E-prescribing has grown rapidly since the DEA published its Interim Final Rule on electronic prescribing of controlled substances (EPCS) in June 2010, not only because the technology has improved, but because of the substantial benefits for patients and physicians. Every state in the U.S. now allows e-prescribing, and many states are mandating EPCS and prescription drug monitoring programs (PDMPs) for all controlled substances. New York mandated e-prescribing for both controlled and non-controlled substances effective March 27, 2016. See how DrFirst can help you comply with state mandates.

Please read our original blog post below.

New York providers need to be aware of the two key requirements in order to comply with coming I-STOP mandate deadlines:

E-prescribing Requirement

All prescriptions for both legend and controlled drugs in the state of New York must be sent electronically (e-prescribed) by March 27, 2016. Electronic prescribing for controlled substances must be supported by two-factor authentication. To satisfy this requirement, there are two steps you must take:

Step 1: Acquire an e-prescribing application that meets federal requirements included in the Drug Enforcement Administration Interim Final Rule regarding Electronic Prescriptions for Controlled Substances. This process requires that each prescriber pass an identity authentication process.

Step 2: Register your e-prescribing application with the Bureau of Narcotic Enforcement online: You may also email the completed Practitioner EPCS Registration (DOH-5121) form to with “Practitioner EPCS Registration” in the subject line.

PMP Query Requirement

All New York providers must query the state Prescription Monitoring Program (PMP) before prescribing controlled substances.

Step 1: Apply for an HCS Medical Professionals Account at

Step 2: Enroll Your Account on the HCS

Step 3: Query the Prescription Monitoring System prior to writing any e-prescription for Schedule II-IV controlled substances

Be sure to bookmark our I-STOP Resources Page to stay on top of any changes to the mandate.

Need Additional Help?

For helping finding the best application for e-prescribing of controlled substances for your practice, visit our EPCS Gold product page or give us a call at (888) 271-9898.
For assistance in obtaining an HCS account, download instructions at: or contact the Commerce Accounts Management Unit at: 1-866-529-1890, Option 2.
For password and account questions: 1-866-529-1890 or email:
For Health Commerce System Technical Help, such as login issues, email:

About pkaufman

Schooled at MIT, Dr. Kaufman nurtured a strong interest in medical informatics while a Bowman Gray School of Medicine faculty member. After entering private practice he founded PiNK software in 1996 to produce EMR software, later becoming DrFirst’s chief medical officer upon its founding. He lectures nationally on various healthcare IT topics, and as a board certified gastroenterologist, he continues a limited clinical practice. Dr. Kaufman is a member of the Health IT Standards Committee, Privacy and Security Workgroup for ONC (Office of the National Coordinator for Healthcare Information Technology). Representing the American Gastroenterology Association’s (AGA), Dr. Kaufman is a delegate to the AMA and was the co-chair of the Physicians Electronic Health Record Consortium (PEHRC). He has participated on workgroups at CCHIT (stand-alone e-prescribing), HIMSS (e-prescribing), and NCPDP (e-prescribing).