September 1, 2015


How To Comply With New York I-STOP

New York providers need to be aware of the two key requirements in order to comply with coming I-STOP mandate deadlines:

E-prescribing Requirement

All prescriptions for both legend and controlled drugs in the state of New York must be sent electronically (e-prescribed) by March 27, 2016. Electronic prescribing for controlled substances must be supported by two-factor authentication. To satisfy this requirement, there are two steps you must take:

Step 1: Acquire an e-prescribing application that meets federal requirements included in the Drug Enforcement Administration Interim Final Rule regarding Electronic Prescriptions for Controlled Substances. This process requires that each prescriber pass an identity authentication process.

Step 2: Register your e-prescribing application with the Bureau of Narcotic Enforcement online: You may also email the completed Practitioner EPCS Registration (DOH-5121) form to with “Practitioner EPCS Registration” in the subject line.

PMP Query Requirement

All New York providers must query the state Prescription Monitoring Program (PMP) before prescribing controlled substances.

Step 1: Apply for an HCS Medical Professionals Account at

Step 2: Enroll Your Account on the HCS

Step 3: Query the Prescription Monitoring System prior to writing any e-prescription for Schedule II-IV controlled substances

Be sure to bookmark our I-STOP Resources Page to stay on top of any changes to the mandate.

Need Additional Help?

For helping finding the best application for e-prescribing of controlled substances for your practice, visit our EPCS Gold product page or give us a call at (888) 271-9898.
For assistance in obtaining an HCS account, download instructions at: or contact the Commerce Accounts Management Unit at: 1-866-529-1890, Option 2.
For password and account questions: 1-866-529-1890 or email:
For Health Commerce System Technical Help, such as login issues, email: